eLife selects outstanding papers for 2013

Drug Resistance

In a bid to shake up the luxury journal cabal, the journal eLife was launched in late 2012 to give researchers a high-quality open-access publishing option that, in addition to having a world-class editorial board, also supports early career scientists and provides open and rigorous peer review. For the second half of 2013, the academic editors of eLife chose five …

The battle against drug resistance just got tougher

Drug Resistance

Do we have any leverage against drug-resistant organisms?   Our post on the Wellcome Trust blog explores the importance of the “fitness cost of drug resistance”. Two studies in 2013 gave notice that our normal expectation — that drug-resistant populations will revert to sensitivity when the selective environment is removed — doesn’t hold true for all pathogens. In mouse and …